| 1 | Sat 17 Oct 2020 | 52-0 v Celta VigoCelta Vigo 0-2 Atlético Madrid | Spanish La Liga |
| 2 | Wed 21 Oct 2020 | 5 0-4 v Bayern MunichBayern Munich 4-0 Atlético Madrid | UEFA Champions League Group A |
| 3 | Sat 24 Oct 2020 | 52-0 v Real BetisAtlético Madrid 2-0 Real Betis | Spanish La Liga |
| 4 | Tue 27 Oct 2020 | 53-2 v SV Red Bull SalzburgAtlético Madrid 3-2 SV Red Bull Salzburg | UEFA Champions League Group A |
| 5 | Sat 31 Oct 2020 | 53-1 v OsasunaOsasuna 1-3 Atlético Madrid | Spanish La Liga |
| 6 | Tue 3 Nov 2020 | 51-1 v Lokomotiv MoscowLokomotiv Moscow 1-1 Atlético Madrid | UEFA Champions League Group A |
| 7 | Sat 7 Nov 2020 | 54-0 v CádizAtlético Madrid 4-0 Cádiz | Spanish La Liga |
| 8 | Sat 5 Dec 2020 | 52-0 v Real ValladolidAtlético Madrid 2-0 Real Valladolid | Spanish La Liga |
| 9 | Wed 9 Dec 2020 | 52-0 v SV Red Bull SalzburgSV Red Bull Salzburg 0-2 Atlético Madrid | UEFA Champions League Group A |
| 10 | Wed 30 Dec 2020 | 51-0 v GetafeAtlético Madrid 1-0 Getafe | Spanish La Liga |
| 11 | Tue 12 Jan 2021 | 52-0 v SevillaAtlético Madrid 2-0 Sevilla | Spanish La Liga |
| 12 | Thu 21 Jan 2021 | 52-1 v EibarEibar 1-2 Atlético Madrid | Spanish La Liga |
| 13 | Sun 24 Jan 2021 | 53-1 v ValenciaAtlético Madrid 3-1 Valencia | Spanish La Liga |
| 14 | Sun 31 Jan 2021 | 5 4-2 v CádizCádiz 2-4 Atlético Madrid | Spanish La Liga |
| 15 | Mon 8 Feb 2021 | 52-2 v Celta VigoAtlético Madrid 2-2 Celta Vigo | Spanish La Liga |
| 16 | Wed 17 Feb 2021 | 51-1 v LevanteLevante 1-1 Atlético Madrid | Spanish La Liga |
| 17 | Sat 20 Feb 2021 | 50-2 v LevanteAtlético Madrid 0-2 Levante | Spanish La Liga |
| 18 | Tue 23 Feb 2021 | 50-1 v ChelseaAtlético Madrid 0-1 Chelsea | UEFA Champions League Round of 16 |
| 19 | Sun 28 Feb 2021 | 52-0 v VillarrealVillarreal 0-2 Atlético Madrid | Spanish La Liga |
| 20 | Wed 10 Mar 2021 | 52-1 v Athletic BilbaoAtlético Madrid 2-1 Athletic Bilbao | Spanish La Liga |
| 21 | Sun 11 Apr 2021 | 51-1 v Real BetisReal Betis 1-1 Atlético Madrid | Spanish La Liga |
| 22 | Sun 18 Apr 2021 | 55-0 v EibarAtlético Madrid 5-0 Eibar | Spanish La Liga |
| 23 | Thu 22 Apr 2021 | 52-0 v HuescaAtlético Madrid 2-0 Huesca | Spanish La Liga |
| 24 | Sun 25 Apr 2021 | 5 1-2 v Athletic BilbaoAthletic Bilbao 2-1 Atlético Madrid | Spanish La Liga |
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