| 1 | Sat 7 Aug 2021 | 192-1 v Doncaster RoversDoncaster Rovers 1-2 AFC Wimbledon | Sky Bet League One |
| 2 | Tue 10 Aug 2021 | 191-0 v Charlton AthleticCharlton Athletic 0-1 AFC Wimbledon | Carabao Cup First Round |
| 3 | Sat 14 Aug 2021 | 193-3 v Bolton WanderersAFC Wimbledon 3-3 Bolton Wanderers | Sky Bet League One |
| 4 | Tue 17 Aug 2021 | 191-1 v GillinghamAFC Wimbledon 1-1 Gillingham | Sky Bet League One |
| 5 | Sat 21 Aug 2021 | 190-1 v SunderlandSunderland 1-0 AFC Wimbledon | Sky Bet League One |
| 6 | Tue 24 Aug 2021 | 19 1-0 v Northampton TownNorthampton Town 0-1 AFC Wimbledon | Carabao Cup Second Round |
| 7 | Sat 28 Aug 2021 | 192-2 v Ipswich TownIpswich Town 2-2 AFC Wimbledon | Sky Bet League One |
| 8 | Sat 4 Sep 2021 | 193-1 v Oxford UnitedAFC Wimbledon 3-1 Oxford United | Sky Bet League One |
| 9 | Tue 7 Sep 2021 | 195-3 v PortsmouthAFC Wimbledon 5-3 Portsmouth | Papa John’s Trophy |
| 10 | Sat 11 Sep 2021 | 194-3 v MorecambeMorecambe 3-4 AFC Wimbledon | Sky Bet League One |
| 11 | Sat 18 Sep 2021 | 190-1 v Plymouth ArgyleAFC Wimbledon 0-1 Plymouth Argyle | Sky Bet League One |
| 12 | Wed 22 Sep 2021 | 190-3 v ArsenalArsenal 3-0 AFC Wimbledon | Carabao Cup Third Round |
| 13 | Sat 25 Sep 2021 | 191-2 v Shrewsbury TownShrewsbury Town 2-1 AFC Wimbledon | Sky Bet League One |
| 14 | Tue 28 Sep 2021 | 19 0-3 v Rotherham UnitedRotherham United 3-0 AFC Wimbledon | Sky Bet League One |
| 15 | Sat 2 Oct 2021 | 191-1 v Burton AlbionAFC Wimbledon 1-1 Burton Albion | Sky Bet League One |
| 16 | Tue 19 Oct 2021 | 19 1-0 v Lincoln CityLincoln City 0-1 AFC Wimbledon | Sky Bet League One |
| 17 | Sat 23 Oct 2021 | 190-2 v Wigan AthleticAFC Wimbledon 0-2 Wigan Athletic | Sky Bet League One |
| 18 | Sat 30 Oct 2021 | 190-1 v Cambridge UnitedCambridge United 1-0 AFC Wimbledon | Sky Bet League One |
| 19 | Sat 6 Nov 2021 | 191-0 v GuiseleyAFC Wimbledon 1-0 Guiseley | Emirates FA Cup First Round |
| 20 | Sat 20 Nov 2021 | 191-2 v PortsmouthPortsmouth 2-1 AFC Wimbledon | Sky Bet League One |
| 21 | Tue 23 Nov 2021 | 193-2 v Crewe AlexandraAFC Wimbledon 3-2 Crewe Alexandra | Sky Bet League One |
| 22 | Sat 27 Nov 2021 | 192-2 v Fleetwood TownAFC Wimbledon 2-2 Fleetwood Town | Sky Bet League One |
| 23 | Sat 4 Dec 2021 | 194-3 v Cheltenham TownAFC Wimbledon 4-3 Cheltenham Town | Emirates FA Cup Second Round |
| 24 | Sat 11 Dec 2021 | 192-2 v Wycombe WanderersWycombe Wanderers 2-2 AFC Wimbledon | Sky Bet League One |
| 25 | Tue 22 Feb 2022 | 190-0 v GillinghamGillingham 0-0 AFC Wimbledon | Sky Bet League One |
| 26 | Sat 26 Feb 2022 | 192-2 v Doncaster RoversAFC Wimbledon 2-2 Doncaster Rovers | Sky Bet League One |
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