| 1 | Sun 6 Feb 2022 | 2 0-1 v Boreham WoodAFC Bournemouth 0-1 Boreham Wood | Emirates FA Cup Fourth Round |
| 2 | Wed 9 Feb 2022 | 23-1 v Birmingham CityAFC Bournemouth 3-1 Birmingham City | Sky Bet Championship |
| 3 | Sat 12 Feb 2022 | 22-1 v BlackpoolBlackpool 1-2 AFC Bournemouth | Sky Bet Championship |
| 4 | Sat 5 Mar 2022 | 21-2 v Preston North EndPreston North End 2-1 AFC Bournemouth | Sky Bet Championship |
| 5 | Tue 8 Mar 2022 | 21-1 v Peterborough UnitedAFC Bournemouth 1-1 Peterborough United | Sky Bet Championship |
| 6 | Sat 12 Mar 2022 | 22-0 v Derby CountyAFC Bournemouth 2-0 Derby County | Sky Bet Championship |
| 7 | Tue 15 Mar 2022 | 21-1 v ReadingAFC Bournemouth 1-1 Reading | Sky Bet Championship |
| 8 | Sat 19 Mar 2022 | 23-0 v Huddersfield TownHuddersfield Town 0-3 AFC Bournemouth | Sky Bet Championship |
| 9 | Sat 2 Apr 2022 | 23-2 v Bristol CityAFC Bournemouth 3-2 Bristol City | Sky Bet Championship |
| 10 | Wed 6 Apr 2022 | 20-2 v West Bromwich AlbionWest Bromwich Albion 2-0 AFC Bournemouth | Sky Bet Championship |
| 11 | Sat 9 Apr 2022 | 20-0 v Sheffield UnitedSheffield United 0-0 AFC Bournemouth | Sky Bet Championship |
| 12 | Fri 15 Apr 2022 | 20-0 v MiddlesbroughAFC Bournemouth 0-0 Middlesbrough | Sky Bet Championship |
| 13 | Mon 18 Apr 2022 | 23-0 v Coventry CityCoventry City 0-3 AFC Bournemouth | Sky Bet Championship |
| 14 | Sat 23 Apr 2022 | 2 1-1 v FulhamAFC Bournemouth 1-1 Fulham | Sky Bet Championship |
| 15 | Tue 26 Apr 2022 | 2 3-3 v Swansea CitySwansea City 3-3 AFC Bournemouth | Sky Bet Championship |
| 16 | Sat 30 Apr 2022 | 2 3-0 v Blackburn RoversBlackburn Rovers 0-3 AFC Bournemouth | Sky Bet Championship |
| 17 | Tue 3 May 2022 | 21-0 v Nottingham ForestAFC Bournemouth 1-0 Nottingham Forest | Sky Bet Championship |
| 18 | Sat 7 May 2022 | 21-0 v MillwallAFC Bournemouth 1-0 Millwall | Sky Bet Championship |
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