| 1 | Sat 24 Aug | 343-2 v Holstein Kiel1899 Hoffenheim 3-2 Holstein Kiel | German Bundesliga |
| 2 | Wed 25 Sep | 341-1 v FC MidtjyllandFC Midtjylland 1-1 1899 Hoffenheim | UEFA Europa League Matchday 1 |
| 3 | Sun 29 Sep | 34 3-4 v Werder Bremen1899 Hoffenheim 3-4 Werder Bremen | German Bundesliga |
| 4 | Thu 3 Oct | 342-0 v Dynamo Kiev1899 Hoffenheim 2-0 Dynamo Kiev | UEFA Europa League Matchday 2 |
| 5 | Thu 24 Oct | 34 0-2 v FC PortoFC Porto 2-0 1899 Hoffenheim | UEFA Europa League Matchday 3 |
| 6 | Sun 27 Oct | 340-0 v 1 FC Heidenheim1 FC Heidenheim 0-0 1899 Hoffenheim | German Bundesliga |
| 7 | Sat 2 Nov | 340-2 v FC St Pauli1899 Hoffenheim 0-2 FC St Pauli | German Bundesliga |
| 8 | Sat 23 Nov | 344-3 v RB Leipzig1899 Hoffenheim 4-3 RB Leipzig | German Bundesliga |
| 9 | Sun 1 Dec | 340-2 v Mainz 05Mainz 05 2-0 1899 Hoffenheim | German Bundesliga |
| 10 | Sun 8 Dec | 341-1 v SC Freiburg1899 Hoffenheim 1-1 SC Freiburg | German Bundesliga |
| 11 | Thu 12 Dec | 340-0 v Steaua Bucharest1899 Hoffenheim 0-0 Steaua Bucharest | UEFA Europa League Matchday 6 |
| 12 | Sun 15 Dec | 341-1 v Borussia DortmundBorussia Dortmund 1-1 1899 Hoffenheim | German Bundesliga |
| 13 | Sat 21 Dec | 341-2 v Borussia Mönchengladbach1899 Hoffenheim 1-2 Borussia Mönchengladbach | German Bundesliga |
| 14 | Sat 11 Jan | 340-1 v VfL Wolfsburg1899 Hoffenheim 0-1 VfL Wolfsburg | German Bundesliga |
| 15 | Wed 15 Jan | 340-5 v Bayern MunichBayern Munich 5-0 1899 Hoffenheim | German Bundesliga |
| 16 | Sat 18 Jan | 343-1 v Holstein KielHolstein Kiel 1-3 1899 Hoffenheim | German Bundesliga |
| 17 | Thu 23 Jan | 342-3 v Tottenham Hotspur1899 Hoffenheim 2-3 Tottenham Hotspur | UEFA Europa League Matchday 7 |
| 18 | Sun 2 Feb | 341-3 v Bayer 04 LeverkusenBayer 04 Leverkusen 3-1 1899 Hoffenheim | German Bundesliga |
| 19 | Sun 16 Feb | 343-1 v Werder BremenWerder Bremen 1-3 1899 Hoffenheim | German Bundesliga |
| 20 | Sun 23 Feb | 341-1 v VfB Stuttgart1899 Hoffenheim 1-1 VfB Stuttgart | German Bundesliga |
| 21 | Sat 1 Mar | 341-0 v VfL BochumVfL Bochum 0-1 1899 Hoffenheim | German Bundesliga |
| 22 | Sat 29 Mar | 341-1 v FC Augsburg1899 Hoffenheim 1-1 FC Augsburg | German Bundesliga |
| 23 | Sat 5 Apr | 341-3 v RB LeipzigRB Leipzig 3-1 1899 Hoffenheim | German Bundesliga |
| 24 | Sat 12 Apr | 34 2-0 v Mainz 051899 Hoffenheim 2-0 Mainz 05 | German Bundesliga |
| 25 | Sat 19 Apr | 34 2-3 v SC FreiburgSC Freiburg 3-2 1899 Hoffenheim | German Bundesliga |
| 26 | Sat 26 Apr | 34 2-3 v Borussia Dortmund1899 Hoffenheim 2-3 Borussia Dortmund | German Bundesliga |
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