| 1 | Sat 6 Aug 2022 | 331-3 v Borussia MönchengladbachBorussia Mönchengladbach 3-1 1899 Hoffenheim | German Bundesliga |
| 2 | Sat 13 Aug 2022 | 333-2 v VfL Bochum1899 Hoffenheim 3-2 VfL Bochum | German Bundesliga |
| 3 | Sat 20 Aug 2022 | 33 3-0 v Bayer 04 LeverkusenBayer 04 Leverkusen 0-3 1899 Hoffenheim | German Bundesliga |
| 4 | Sat 27 Aug 2022 | 331-0 v FC Augsburg1899 Hoffenheim 1-0 FC Augsburg | German Bundesliga |
| 5 | Fri 2 Sep 2022 | 330-1 v Borussia DortmundBorussia Dortmund 1-0 1899 Hoffenheim | German Bundesliga |
| 6 | Sat 10 Sep 2022 | 334-1 v Mainz 051899 Hoffenheim 4-1 Mainz 05 | German Bundesliga |
| 7 | Sun 18 Sep 2022 | 330-0 v SC Freiburg1899 Hoffenheim 0-0 SC Freiburg | German Bundesliga |
| 8 | Sun 2 Oct 2022 | 331-1 v Hertha BerlinHertha Berlin 1-1 1899 Hoffenheim | German Bundesliga |
| 9 | Fri 7 Oct 2022 | 331-2 v Werder Bremen1899 Hoffenheim 1-2 Werder Bremen | German Bundesliga |
| 10 | Fri 14 Oct 2022 | 333-0 v FC Schalke 04FC Schalke 04 0-3 1899 Hoffenheim | German Bundesliga |
| 11 | Sat 22 Oct 2022 | 330-2 v Bayern Munich1899 Hoffenheim 0-2 Bayern Munich | German Bundesliga |
| 12 | Sun 30 Oct 2022 | 331-1 v 1 FC Köln1 FC Köln 1-1 1899 Hoffenheim | German Bundesliga |
| 13 | Sat 5 Nov 2022 | 33 1-3 v RB Leipzig1899 Hoffenheim 1-3 RB Leipzig | German Bundesliga |
| 14 | Wed 9 Nov 2022 | 332-4 v Eintracht FrankfurtEintracht Frankfurt 4-2 1899 Hoffenheim | German Bundesliga |
| 15 | Sat 12 Nov 2022 | 331-2 v VfL Wolfsburg1899 Hoffenheim 1-2 VfL Wolfsburg | German Bundesliga |
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