| 1 | Sat 11 Sep 2021 | 290-2 v Mainz 051899 Hoffenheim 0-2 Mainz 05 | German Bundesliga |
| 2 | Sat 18 Sep 2021 | 290-0 v Arminia BielefeldArminia Bielefeld 0-0 1899 Hoffenheim | German Bundesliga |
| 3 | Fri 15 Oct 2021 | 295-0 v 1. FC Köln1899 Hoffenheim 5-0 1. FC Köln | German Bundesliga |
| 4 | Sat 23 Oct 2021 | 290-4 v Bayern MunichBayern Munich 4-0 1899 Hoffenheim | German Bundesliga |
| 5 | Fri 29 Oct 2021 | 292-0 v Hertha Berlin1899 Hoffenheim 2-0 Hertha Berlin | German Bundesliga |
| 6 | Sat 6 Nov 2021 | 290-2 v VfL BochumVfL Bochum 2-0 1899 Hoffenheim | German Bundesliga |
| 7 | Sun 10 Apr 2022 | 290-3 v RB LeipzigRB Leipzig 3-0 1899 Hoffenheim | German Bundesliga |
| 8 | Sun 17 Apr 2022 | 290-0 v Greuther Fürth1899 Hoffenheim 0-0 Greuther Fürth | German Bundesliga |
| 9 | Sat 23 Apr 2022 | 29 2-2 v Eintracht FrankfurtEintracht Frankfurt 2-2 1899 Hoffenheim | German Bundesliga |
| 10 | Sat 30 Apr 2022 | 293-4 v SC Freiburg1899 Hoffenheim 3-4 SC Freiburg | German Bundesliga |
| 11 | Sat 7 May 2022 | 292-4 v Bayer 04 Leverkusen1899 Hoffenheim 2-4 Bayer 04 Leverkusen | German Bundesliga |
| 12 | Sat 14 May 2022 | 291-5 v Borussia MönchengladbachBorussia Mönchengladbach 5-1 1899 Hoffenheim | German Bundesliga |
| 13 | Fri 10 Jun 2022 | 120-1 v CroatiaDenmark 0-1 Croatia | UEFA Nations League League A Group 1 |
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