| 1 | Sun 7 Aug 2022 | 333-1 v FC Schalke 041 FC Köln 3-1 FC Schalke 04 | German Bundesliga |
| 2 | Sat 13 Aug 2022 | 332-2 v RB LeipzigRB Leipzig 2-2 1 FC Köln | German Bundesliga |
| 3 | Thu 18 Aug 2022 | 331-2 v Videoton FC Fehervar1 FC Köln 1-2 Videoton FC Fehervar | UEFA Europa Conference League Play-off |
| 4 | Sun 21 Aug 2022 | 33 1-1 v Eintracht FrankfurtEintracht Frankfurt 1-1 1 FC Köln | German Bundesliga |
| 5 | Thu 25 Aug 2022 | 333-0 v Videoton FC FehervarVideoton FC Fehervar 0-3 1 FC Köln | UEFA Europa Conference League Play-off |
| 6 | Sun 28 Aug 2022 | 330-0 v VfB Stuttgart1 FC Köln 0-0 VfB Stuttgart | German Bundesliga |
| 7 | Thu 8 Sep 2022 | 331-1 v NiceNice 1-1 1 FC Köln | UEFA Europa Conference League Group D |
| 8 | Sun 11 Sep 2022 | 330-1 v 1 FC Union Berlin1 FC Köln 0-1 1 FC Union Berlin | German Bundesliga |
| 9 | Thu 15 Sep 2022 | 334-2 v Slovácko1 FC Köln 4-2 Slovácko | UEFA Europa Conference League Group D |
| 10 | Sun 18 Sep 2022 | 331-1 v VfL BochumVfL Bochum 1-1 1 FC Köln | German Bundesliga |
| 11 | Sat 1 Oct 2022 | 333-2 v Borussia Dortmund1 FC Köln 3-2 Borussia Dortmund | German Bundesliga |
| 12 | Thu 6 Oct 2022 | 330-1 v FK Partizan1 FC Köln 0-1 FK Partizan | UEFA Europa Conference League Group D |
| 13 | Sun 9 Oct 2022 | 332-5 v Borussia MönchengladbachBorussia Mönchengladbach 5-2 1 FC Köln | German Bundesliga |
| 14 | Thu 13 Oct 2022 | 330-2 v FK PartizanFK Partizan 2-0 1 FC Köln | UEFA Europa Conference League Group D |
| 15 | Sun 16 Oct 2022 | 333-2 v FC Augsburg1 FC Köln 3-2 FC Augsburg | German Bundesliga |
| 16 | Fri 21 Oct 2022 | 330-5 v Mainz 05Mainz 05 5-0 1 FC Köln | German Bundesliga |
| 17 | Sun 30 Oct 2022 | 331-1 v 1899 Hoffenheim1 FC Köln 1-1 1899 Hoffenheim | German Bundesliga |
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